Game silently exits on proton versions 7.x+ and not all installation steps take place, product registration screen doesn't appear for example, changing proton compatibility version is sufficient to resolve this issue.

Most problems with the game stem from the game itself. Keyboard and mouse is required until the options menu allows you to change input device. The game only properly supports Xbox 360 pads - Xbox One and Xbox Series X gamepads have incorrect bindings and serious limitations on rebinding.

Default bindings puts looking left and right on LT/RT. None of the face buttons are correctly mapped. Default 360 bindings can not be achieved as Target Lock and High Profile can not be bound to LT and RT respectively, one can substitute for LB and RB, although this is a noticeably less comfortable position to hold the controller in longer play sessions.

Steam input didn't appear to work at all for me, controller bindings just completely failed to take effect, although this may be an issue specific to my system - your mileage may vary.

Normal recommendations apply, enable vsync to avoid physics bugs. Swap out intro videos to skip long intro scene.