Devil May Cry 4 
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JimnorRain (5 reports)
< 1 hour overallWorks out of the box
I didn't test launching it with the DX10 version but the base game is flawless without any glitches / crashes or artifacting.
Proton 8.0-4
Distro:EndeavourOS Linux
Kernel:6.6.8-arch1-1
RAM:32 GB
GPU Driver:4.6 Mesa 23.3.1-arch1.1
GPU:AMD Radeon RX 6700 XT (radeonsi, navi22, LLVM 16.0.6, DRM 3.54, 6.6.8-arch1-1)
CPU:AMD Ryzen 7 5700X 8-Core
Proton 8.0-4
Distro:EndeavourOS Linux
Kernel:6.6.8-arch1-1
RAM:32 GB
GPU Driver:4.6 Mesa 23.3.1-arch1.1
GPU:AMD Radeon RX 6700 XT (radeonsi, navi22, LLVM 16.0.6, DRM 3.54, 6.6.8-arch1-1)
CPU:AMD Ryzen 7 5700X 8-Core
Nuclear Kangaroo (65 reports)
3 hours overall
Tinker Steps:Custom Proton
the game seems to run great running on Proton 8, recommended
Custom Proton:
Distro:SteamOS Holo
Kernel:5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb
RAM:15 GB
GPU Driver:4.6 Mesa 22.0.0-devel (git-676ccacebc)
GPU:AMD Custom GPU 0405 (vangogh, LLVM 13.0.0, DRM 3.45, 5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb)
CPU:AMD Custom APU 0405
Custom Proton:
Distro:SteamOS Holo
Kernel:5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb
RAM:15 GB
GPU Driver:4.6 Mesa 22.0.0-devel (git-676ccacebc)
GPU:AMD Custom GPU 0405 (vangogh, LLVM 13.0.0, DRM 3.45, 5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb)
CPU:AMD Custom APU 0405
ThreeSon (791 reports)
Graphics:Other
Pre-rendered videos are all broken
Save Games:Other
Save data is deleted when the game is uninstalled
Proton 7.0-3
Distro:SteamOS Holo
Kernel:5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb
RAM:15 GB
GPU Driver:4.6 Mesa 22.0.0-devel (git-676ccacebc)
GPU:AMD Custom GPU 0405 (vangogh, LLVM 13.0.0, DRM 3.45, 5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb)
CPU:AMD Custom APU 0405
Proton 7.0-3
Distro:SteamOS Holo
Kernel:5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb
RAM:15 GB
GPU Driver:4.6 Mesa 22.0.0-devel (git-676ccacebc)
GPU:AMD Custom GPU 0405 (vangogh, LLVM 13.0.0, DRM 3.45, 5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb)
CPU:AMD Custom APU 0405
Jenya(671 reports)
Jenya (671 reports)
Installs:Yes
Opens:No
Proton 7.0-2
Jenya(671 reports)
Proton 7.0-2
A full play through with turbo on no input lag or issues, save minor camera issues in vertical shafts.
Significant Bugs:Yes
Direct x 10 crashes when launching, and Direct X9 has camera transition issues in long vertical shafts such as M5, M6, and M15
Proton 5.0-9
Distro:Manjaro Linux
Kernel:5.8.6-1-MANJARO
RAM:16 GB
GPU Driver:NVIDIA 450.66
GPU:NVIDIA GeForce RTX 2060
CPU:AMD Ryzen 5 3600 6-Core
Proton 5.0-9
Distro:Manjaro Linux
Kernel:5.8.6-1-MANJARO
RAM:16 GB
GPU Driver:NVIDIA 450.66
GPU:NVIDIA GeForce RTX 2060
CPU:AMD Ryzen 5 3600 6-Core
DanVJ (25 reports)
(an hour with Proton)Platinum
Max settings run perfectly out of the box with Direct X 10
Distro:Linux
Kernel:5.1.14-arch1-1-ARCH
RAM:32 GB
GPU Driver:NVIDIA 430.26
GPU:NVIDIA GeForce GTX 1060 6GB
CPU:Intel Core i7-6700K @ 4.00GHz
Distro:Linux
Kernel:5.1.14-arch1-1-ARCH
RAM:32 GB
GPU Driver:NVIDIA 430.26
GPU:NVIDIA GeForce GTX 1060 6GB
CPU:Intel Core i7-6700K @ 4.00GHz
Laudrac (199 reports)
(an hour with Proton)Platinum
Just works perfect with a controller
Distro:SteamOS 2.0
Kernel:4.16.0-0.steamos2.1-amd64
RAM:16 GB
GPU Driver:NVIDIA 396.54
GPU:NVIDIA GeForce GTX 1080 Ti
CPU:Intel Core i7-7700K @ 4.20GHz
Distro:SteamOS 2.0
Kernel:4.16.0-0.steamos2.1-amd64
RAM:16 GB
GPU Driver:NVIDIA 396.54
GPU:NVIDIA GeForce GTX 1080 Ti
CPU:Intel Core i7-7700K @ 4.20GHz
Ranilen (4 reports)
(< 15 minutes with Proton)Platinum
Graphics, sound, and controller support are all flawless out of the box.
Distro:Manjaro Linux
Kernel:4.19.20-1-MANJARO
RAM:16 GB
GPU Driver:NVIDIA 390.87
GPU:NVIDIA GeForce GTX 670M
CPU:Intel Core i7-3720QM @ 2.60GHz
Distro:Manjaro Linux
Kernel:4.19.20-1-MANJARO
RAM:16 GB
GPU Driver:NVIDIA 390.87
GPU:NVIDIA GeForce GTX 670M
CPU:Intel Core i7-3720QM @ 2.60GHz
UnknownUnknown
Platinum
It just runs perfectly. Gamepad detected and well configured. Maxed the game and benchmark kept hovering around 250-300 fps. Played two missions withour problems. Should be whitelisted.
Distro:Linux Mint 19 Tara
Kernel:4.15.0-34-generic
RAM:16 GB
GPU Driver:NVIDIA 396.54.05
GPU:NVIDIA GeForce GTX 970
CPU:Intel Core i5-4670K @ 3.40GHz
UnknownDistro:Linux Mint 19 Tara
Kernel:4.15.0-34-generic
RAM:16 GB
GPU Driver:NVIDIA 396.54.05
GPU:NVIDIA GeForce GTX 970
CPU:Intel Core i5-4670K @ 3.40GHz
UnknownUnknown
Silver
Played through the tutorial missions without a problem.
Distro:Arch Linux (4.18.5-arch1-1-ARCH)
GPU Driver:NVIDIA 396.54-2
UnknownDistro:Arch Linux (4.18.5-arch1-1-ARCH)
GPU Driver:NVIDIA 396.54-2
UnknownUnknown
Silver
Roughly 1/6th the frame rate of native Windows - benchmarks : https://appdb.winehq.org/objectManager.php?sClass=version&iId=20952
Distro:Xubuntu 18.04
GPU Driver:AMDGPU Mesa 18.1.6-1~b~padoka0
UnknownDistro:Xubuntu 18.04
GPU Driver:AMDGPU Mesa 18.1.6-1~b~padoka0
