cyclosa
Published
occasional screen tearing, not hugely annoying for this type of game
The native port does not support achievements, so you have to run the Windows version in Proton if you want them. The game crashes during the intro with Proton 5, but it works in 4.11-13.
(Note: as far as I can tell, save files are not cross-compatible between the Linux and Proton versions)
Broken
Silently crashed without creating a window. Tried every available Proton version, including 3.16 which a previous report said was playable.
With default configuration, Vessel crashed on Alt-Tab. This is fixable with this tweak:
env WINEPREFIX=<STEAM_PATH>/steamapps/compatdata/108500/pfx winecfg
Go to the Graphics tab and enable "Emulate a virtual desktop"
When the game was minimized, Vessel's custom mouse cursor flickered over my system mouse for around a minute until the game simply crashed. The tweak mentioned above also fixed this.
Sometimes crashes if you open the Steam overlay during the startup loading screen - avoid doing this and you should be fine (the overlay works fine otherwise)
Other than possible crashes (which may or may not be from Proton), runs just as well as native.
Crashed once. Not totally sure if it's a Proton issue, because there are reports of occasional crashes on Windows too.