Some voice lines would get cut off prematurely and other voice lines would be spoken over the top of them, particularly when in battle and opening treasure chests. I don't have a way to test it, so this may be a matter of game design, rather than a Linux exclusive problem.

Water textures in Rhata Harbor would occasionally visibly glitch and stutter, presenting a gray pixellation pattern of artifacts that overlayed other visual elements on the screen (plants, structures, etc.) Particularly noticeable when looking out into the distance of the ocean with some camera angles and positions around the town.

I used a wired Xbox 360 controller playing via the docking station and it worked pretty well. The only issue I had was the options menu felt too sensitive to even slight left/right movements, causing options to be changed accidentally when just trying to scroll up/down the menu. The "reset to defaults" setting was very helpful for this.