
Works out of the box
My wife and I are currently playing through Nikoderiko together on my PC with Xbox controllers (Generic PowerA controllers). We started the game on the 26th with a relatively short session around 3.6 hours in total so far.
We did have one hiccup, although I did not include it in my report yet. At one point, we lost responsiveness from our controllers in a sporadic manner. I'm not positive what might have happened at the point and time, and it might have even been something I did. I didn't include it because it happened once early on in our start of the game, and I haven't been able to duplicate it again thus far.
Game run perfectly out of the box. I was able to play it with highest graphic settings in 4K with 144Hz easily.

After today's patch (January 10th), i played around 3 hours and the game no longer has the stuttering issue!
I finished the main story, my save game is at 80% completed, and it ran great :)

Game runs perfectly fine, only has the ocasinal stutter (probably due to Denuvo)
Ocasional Stutter with no apparent reason. Game was set to it's default 120 FPS